About macular pigment/Introducing Retiortein
It is estimated that over 600 types of rotenoids have been isolated and characterized in nature. Among these, it is said that there are 40 to 50 types of rotenoids that are contained in foods such as vegetables and fruits that we eat every day [1.2]. It has been previously discovered that of the large number of cylindrical tenoids derived from such dietary crystals, only two types, lutein and zeaxanthin, exist in the central part of the retina, which controls our vision, namely the macula (Figure 1). (excluding metabolites produced in the body) [3]. Since the yellow pigments in the macula (macular pigment) are mainly lutein and zeaxanthin, there are some documents that refer to them as macular rottenoids.
A total of 4,200 participants with age-related macular degeneration (AMD) were enrolled in a five-year follow-up study at 85 facilities across the United States under the name AREDS2. The potential benefits of other nutrients were reported in 2013 [5]. The following daily dose recommended in AREDS2 became one of the cornerstones of subsequent supplement design.
Lutein is abundant in dark green leaves such as kale and spinach, while zeaxanthin is present in plant sources such as corn and persimmons, as well as animal eggs in concentrations comparable to those in vegetables and fruits. is recognized. Commercial use of macular rotenoids has been achieved through extraction and purification from marigold (Tagetes erecta L.) petals (Figure 2) [4]. Naturally ™ Retio Lutein® contains XanMax® , the flagship product of Chikaratrafitchem*. Zanmax® is a high-grade lutein and zeaxanthin product obtained from marigold using the company's patented manufacturing method (JP4848420).
Detailed information
Retio Lutein®
| name | Processed foods containing lutein |
|---|---|
| Raw material name | Gelatin, olive oil, vegetable oil containing vitamin E, yeast containing zinc/vitamin C, glycerin, glycerin fatty acid ester, beeswax, marigold pigment |
| Internal capacity | 40.5g (1 tablet weight 450mg x 90 tablets) |
| Preservation method | Please store away from direct sunlight and places with high temperature and humidity. |
Nutrition information/3 tablets (1.35g) per day
Energy: 7.71 kcal, protein: 0.35 g, fat: 0.53 g, carbohydrate: 0.38 g, salt equivalent: 0.0035 g, vitamin C 240 mg, vitamin E 134 mg, zinc 15 mg
Lutein 10mg, zeaxanthin 2mg
Precautions for intake
● This product does not cure diseases or improve health by consuming large amounts. ● Please follow the recommended daily intake amount. ● Please keep out of reach of infants. ● Since we use naturally derived raw materials, the color and odor may change, but this does not affect the quality. ● Please refer to the ingredients and consult your doctor or pharmacist if you have a food allergy. ● Please handle with care and hygiene. ● Please consume as soon as possible after opening.
A balanced diet is based on staple foods, main dishes, and side dishes.
■References
- Schalch W. Carotenoids in the retina--a review of their possible role in preventing or limiting damage caused by light and oxygen. EXS. 1992;62:280-98.
- Khachik F, et al. Distribution of carotenoids in fruits and vegetables as a criterion for the selection of appropriate chemopreventive agents. In: Yoshikawa T, Ohigashi H, eds. Food Factors for Cancer Prevention. Tokyo: Springer-Verlag; 1997:204- 8.
- Bone RA, Landrum JT, Tarsis SL. Preliminary identification of the human macular pigment. Vision Res. 1985;25(11):1531-5.
- Bernstein P. Studies related to the protective role of dietary carotenoids. Lutein and Zeaxanthin against AMD. Abstract presented at SupplySide® West. 15. November 2013.
- The Age-Related Eye Disease Study 2 (AREDS2) Research Group. Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration. The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial. JAMA. 2013 May 15 :309(19):2005-15.
